General Information


DRAVP ID  DRAVPe02692

Peptide Name   -

Sequence  CQLPAERWC

Sequence Length  9

UniProt ID  No Entry Found 

Taxon ID  None

Source  Phage display

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  SNV

Assay  Focus reduction assay

Activity 

  • [Ref:15919886]SNV:IC50=9.1 × 10^8 particles/μl

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  beta-3 integrins

Mechanism  Not Available



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H122C172N24O35S1

Absent amino acids  HILKMFTWV

Common amino acids  CAR

Mass  2584.891

Pl  4.05002841949462

Basic residues  0

Acidic residues  6

Hydrophobic residues  11

Net charge  -6.03096177194726

Boman Index  0.99

Hydrophobicity  0.113636363636363

Aliphatic Index  97.27

Half Life 

  •     Mammalian:20hours
  •     Yeast:15hours
  •     E.coli:18hours

Extinction Coefficient cystines  11000

Absorbance 280nm  4.25549858775476

Polar residues  11



Literature Information


Literature 1

Title   Peptide antagonists that inhibit Sin Nombre virus and hantaan virus entry through the beta3-integrin receptor.

Pubmed ID   15919886

Reference   J Virol. 2005

Author   Larson RS, Brown DC, Ye C, Hjelle B.

DOI   10.1128/JVI.79.12.7319-7326.2005