General Information
DRAVP ID DRAVPe02695
Peptide Name P2
Sequence KSNVVRGWVFGSTMNNKSQS
Sequence Length 20
UniProt ID P59594
Taxon ID 694009
Source S1 of SARS-CoV spike protein
Validation Experimentally Validated
Origin Information
Gene Name/ID S
GenBank Not Available
Amino Acid position 94–113
Domain Accession ID Not Available
Nucleotide sequence ID AY274119.3
Molecular Type Genomic RNA
Chromosomal Position Chromosome:21,492 - 25,259
Activity Information
Target Organism SARS-CoV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H86C125N25O23S0
Absent amino acids DOYVOU
Common amino acids VN
Mass 1895.0815
Pl 8.50358943939209
Basic residues 4
Acidic residues 2
Hydrophobic residues 6
Net charge 0.848190022559939
Boman Index 1.364
Hydrophobicity -1.26666666666666
Aliphatic Index 52
Half Life
Extinction Coefficient cystines 2980
Absorbance 280nm 1.57249173716275
Polar residues 9
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
Pubmed ID 15811330
Reference FEBS Lett. 2005
Author Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B.