General Information
DRAVP ID DRAVPe02696
Peptide Name P3
Sequence YKGYQPIDVVRDLPSGFNTL
Sequence Length 20
UniProt ID P59594
Taxon ID 694009
Source S1 of SARS-CoV spike protein
Validation Experimentally Validated
Origin Information
Gene Name/ID S
GenBank Not Available
Amino Acid position 197–216
Domain Accession ID Not Available
Nucleotide sequence ID AY274119.3
Molecular Type Genomic RNA
Chromosomal Position Chromosome:21,492 - 25,259
Activity Information
Target Organism SARS-CoV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H206C310N49O69S0
Absent amino acids COU
Common amino acids VY
Mass 4595.9751
Pl 4.12011089324951
Basic residues 4
Acidic residues 9
Hydrophobic residues 15
Net charge -6.16867647522656
Boman Index 0.953
Hydrophobicity -0.502439024390243
Aliphatic Index 87.8
Half Life
Extinction Coefficient cystines 2980
Absorbance 280nm 0.648393417100976
Polar residues 26
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
Pubmed ID 15811330
Reference FEBS Lett. 2005
Author Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B.