General Information
DRAVP ID DRAVPe02697
Peptide Name P4
Sequence TDAVDCSQNPLAELKCSVKSF
Sequence Length 21
UniProt ID P59594
Taxon ID 694009
Source S1 of SARS-CoV spike protein
Validation Experimentally Validated
Origin Information
Gene Name/ID S
GenBank Not Available
Amino Acid position 273–293
Domain Accession ID Not Available
Nucleotide sequence ID AY274119.3
Molecular Type Genomic RNA
Chromosomal Position Chromosome:21,492 - 25,259
Activity Information
Target Organism SARS-CoV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H38C56N14O12S2
Absent amino acids RNWMNYOU
Common amino acids CS
Mass 983.0831
Pl 6.89834384918212
Basic residues 2
Acidic residues 0
Hydrophobic residues 3
Net charge -0.0853519894995431
Boman Index 0.832
Hydrophobicity -0.433333333333333
Aliphatic Index 32.22
Half Life
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
Pubmed ID 15811330
Reference FEBS Lett. 2005
Author Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B.