General Information
DRAVP ID DRAVPe02698
Peptide Name P5
Sequence KGIYQTSNFRVVPSGDVVRF
Sequence Length 20
UniProt ID P59594
Taxon ID 694009
Source S1 of SARS-CoV spike protein
Validation Experimentally Validated
Origin Information
Gene Name/ID S
GenBank Not Available
Amino Acid position 297–316
Domain Accession ID Not Available
Nucleotide sequence ID AY274119.3
Molecular Type Genomic RNA
Chromosomal Position Chromosome:21,492 - 25,259
Activity Information
Target Organism SARS-CoV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H81C127N29O26S0
Absent amino acids ANDCMWYOU
Common amino acids FV
Mass 1943.0848
Pl 6.75533695220947
Basic residues 4
Acidic residues 3
Hydrophobic residues 4
Net charge -0.148701214402215
Boman Index 1.459
Hydrophobicity -1.85999999999999
Aliphatic Index 71.33
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 0.766821911220756
Polar residues 11
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
Pubmed ID 15811330
Reference FEBS Lett. 2005
Author Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B.