General Information
DRAVP ID DRAVPe02699
Peptide Name P6
Sequence TKFPSVYAWERKKISNCVAD
Sequence Length 20
UniProt ID P59594
Taxon ID 694009
Source S1 of SARS-CoV spike protein
Validation Experimentally Validated
Origin Information
Gene Name/ID S
GenBank Not Available
Amino Acid position 332–351
Domain Accession ID Not Available
Nucleotide sequence ID AY274119.3
Molecular Type Genomic RNA
Chromosomal Position Chromosome:21,492 - 25,259
Activity Information
Target Organism SARS-CoV
Assay Syncitia assay
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit Virus entry
Structure Information
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H79C127N23O21S0
Absent amino acids CQMNOU
Common amino acids K
Mass 1753.0103
Pl 8.74786014556885
Basic residues 2
Acidic residues 1
Hydrophobic residues 7
Net charge 0.761903075263511
Boman Index 1.113
Hydrophobicity -0.406666666666666
Aliphatic Index 117.33
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 3.13746017350839
Polar residues 8
Literature Information
Literature 1
Title Synthetic peptides derived from SARS coronavirus S protein with diagnostic and therapeutic potential.
Pubmed ID 15811330
Reference FEBS Lett. 2005
Author Lu W, Wu XD, Shi MD, Yang RF, He YY, Bian C, Shi TL, Yang S, Zhu XL, Jiang WH, Li YX, Yan LC, Ji YY, Lin Y, Lin GM, Tian L, Wang J, Wang HX, Xie YH, Pei G, Wu JR, Sun B.