General Information


DRAVP ID  DRAVPe02701

Peptide Name   SB101

Sequence  QKKIRVRLSA

Sequence Length  10

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic Construct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  HCMV

Assay  EGFP expression

Activity  No MIC is available in the Article

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit the replication of GCV-resistant strains of HCMV



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H73C129N19O16S0

Absent amino acids  CDEFGHIMNPQRSW

Common amino acids  AKLTVY

Mass  1546.93

Pl  10.3016771316528

Basic residues  5

Acidic residues  0

Hydrophobic residues  8

Net charge  4.78988058186008

Boman Index  1.216

Hydrophobicity  2.142

Aliphatic Index  111.43

Half Life 

  •     Mammalian:4.4 hours
  •     Yeast:20 hours
  •     E.coli:10 hours

Extinction Coefficient cystines  1490

Absorbance 280nm  0.963192970475485

Polar residues  6



Literature Information


Literature 1

Title   Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.

Pubmed ID   20083141

Reference   Antiviral Res. 2010

Author   Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G.

DOI   10.1016/j.antiviral.2010103