General Information
DRAVP ID DRAVPe02705
Peptide Name SB105
Sequence ASLRVRIKKQ
Sequence Length 10
UniProt ID No Entry Found
Taxon ID None
Source Synthetic Construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCMV,MCMV
Assay EGFP expression
Activity
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit the replication of GCV-resistant strains of HCMV
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H72C127N17O15S0
Absent amino acids CDEFGHIMNPQRSW
Common amino acids AKLTVY
Mass 1488.89
Pl 10.1768663406372
Basic residues 4
Acidic residues 0
Hydrophobic residues 8
Net charge 3.75510660919429
Boman Index 1.117
Hydrophobicity 0.66
Aliphatic Index 156.92
Half Life
Extinction Coefficient cystines 1490
Absorbance 280nm 17396
Polar residues 5
Literature Information
Literature 1
Title Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.
Pubmed ID 20083141
Reference Antiviral Res. 2010
Author Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G.