General Information


DRAVP ID  DRAVPe02707

Peptide Name   SB106

Sequence  FKKIRVRL

Sequence Length  8

UniProt ID  No Entry Found 

Taxon ID  None

Source  Synthetic Construct

Validation   Experimentally Validated



Origin Information


Gene Name/ID  Not Available

GenBank  Not Available

Amino Acid position  Not Available

Domain Accession ID  Not Available

Nucleotide sequence ID  Not Available

Molecular Type  Not Available

Chromosomal Position  Not Available



Activity Information


Target Organism  HCMV

Assay  EGFP expression

Activity  No MIC is available in the Article

Hemolytic Activity  No hemolysis information or data found in the reference(s) presented in this entry

Cytotoxicity  No cytotoxicity information found in the reference(s) presented

Binding Target  Membrane

Mechanism  Inhibit the replication of GCV-resistant strains of HCMV



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure available

Linear/Cyclic  Linear

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Stereochemistry  L



Physicochemical Information


Formula  H50C88N16O8S0

Absent amino acids  ACDEGHMNPQSTWY

Common amino acids  FIKLRV

Mass  1059.35

Pl  11.9999677658081

Basic residues  4

Acidic residues  0

Hydrophobic residues  4

Net charge  3.75808361239129

Boman Index  1.599

Hydrophobicity  -0.1875

Aliphatic Index  133.75

Half Life 

  •     Mammalian:1.1 hours
  •     Yeast:30 mins
  •     E.coli:54 mins

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  4



Literature Information


Literature 1

Title   Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.

Pubmed ID   20083141

Reference   Antiviral Res. 2010

Author   Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G.

DOI   10.1016/j.antiviral.2010103