General Information
DRAVP ID DRAVPe02710
Peptide Name SB109
Sequence QKKIRVRFSA
Sequence Length 10
UniProt ID No Entry Found
Taxon ID None
Source Synthetic Construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCMV
Assay EGFP expression
Activity No MIC is available in the Article
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit the replication of GCV-resistant strains of HCMV
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H113C167N27O35S1
Absent amino acids ACHKNQW
Common amino acids DEFGILMPRSTVY
Mass 1232.49
Pl 4.55544071197509
Basic residues 2
Acidic residues 3
Hydrophobic residues 9
Net charge -1.59976842457747
Boman Index 0.888
Hydrophobicity -0.39
Aliphatic Index 69.52
Half Life
Extinction Coefficient cystines 4470
Absorbance 280nm 1.77820217713209
Polar residues 12
Literature Information
Literature 1
Title Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.
Pubmed ID 20083141
Reference Antiviral Res. 2010
Author Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G.