General Information
DRAVP ID DRAVPe02712
Peptide Name SB111
Sequence QKKIRIRLSA
Sequence Length 10
UniProt ID No Entry Found
Taxon ID None
Source Synthetic Construct
Validation Experimentally Validated
Origin Information
Gene Name/ID Not Available
GenBank Not Available
Amino Acid position Not Available
Domain Accession ID Not Available
Nucleotide sequence ID Not Available
Molecular Type Not Available
Chromosomal Position Not Available
Activity Information
Target Organism HCMV
Assay EGFP expression
Activity No MIC is available in the Article
Hemolytic Activity No hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity No cytotoxicity information found in the reference(s) presented
Binding Target Membrane
Mechanism Inhibit the replication of GCV-resistant strains of HCMV
Structure Information
PDB ID None
Predicted Structure Download No predicted structure available
Linear/Cyclic Linear
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Stereochemistry L
Physicochemical Information
Formula H68C105N25O21S0
Absent amino acids CDEFIKLMQVY
Common amino acids AGHNPRSTW
Mass 1626.73
Pl 11.9999677658081
Basic residues 3
Acidic residues 0
Hydrophobic residues 4
Net charge 2.456
Boman Index 0.87
Hydrophobicity -1.12
Aliphatic Index 20
Half Life
Extinction Coefficient cystines 5500
Absorbance 280nm 3.38101257761268
Polar residues 11
Literature Information
Literature 1
Title Peptide-derivatized dendrimers inhibit human cytomegalovirus infection by blocking virus binding to cell surface heparan sulfate.
Pubmed ID 20083141
Reference Antiviral Res. 2010
Author Luganini A, Giuliani A, Pirri G, Pizzuto L, Landolfo S, Gribaudo G.