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DRAVP ID DRAVPa0046
Peptide Name Sequence 8 from Patent US 2009/0264344 A1
Sequence GICICICGYGICRCICGR
Sequence Length 18
Source Synthetic construct
Target Organism HIV-1,HSV-1,HSV-2
Patent Type Patent Application
Publication Date 2009-10-22
Patent No US 2009/0264344 A1
Family Info US 2005/0272645 A1, WO 2006/052637 A1, US 7314858 B2, US 2009/0264344 A1, US 7718610 B2
Patent Title Retrocyclins: Antiviral and Antimicrobial Peptides
Comment The peptide is potently active against both X4 and R5 strains of HIV-1 by inhibiting virus replication.
Abstract Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.