Patent Information


DRAVP ID  DRAVPa0307

Peptide Name   Sequence 2 from Patent US 7790171 B1

Sequence  GALFLGFLGAAGSTMGAWSQPKSKRKV

Sequence Length  27

Source  Synthetic construct

Target Organism  HIV

Patent Type  Granted Patent

Publication Date  2010-09-07

Patent No  US 7790171 B1

Family Info  WO 2002/015661 A2, AU 2001/092153 A, WO 2002/015661 A8, WO 2002/015661 A3, EP 1311538 A2, EP 1311538 B1, AT 420103 T, DE 60137340 D1, US 7790171 B1, US 2011/0064793 A1

Patent Title  Antiviral peptides obtained from the tryptophan-rich hydrophobic cluster of the HIV-1 reverse transcriptase

Comment  No comments found in patent

Abstract  The invention is drawn to a novel class of drugs directed against HIV, comprising a peptide or analog comprising a decapeptide, said decapeptide containing (from N-terminus to the C-terminus) a basic amino acid in position 1, an acidic amino acid in positions 2 and 5, and a tryptophan in positions 4, 7, and 8, and to a method of treatment of HIV infections, in particular multidrug-resistant HIV infections.