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DRAVP ID DRAVPa1011
Peptide Name Sequence 28 from Patent US 7432045 B2
Sequence RRKKAAVAVVP
Sequence Length 11
Source Synthetic construct
Target Organism HSV,HIV,Influenza A Virus,H5 Avian Influenza Virus
Patent Type Granted Patent
Publication Date 2008-10-07
Patent No US 7432045 B2
Family Info WO 2005/060541 A2, US 2005/0203024 A1, WO 2005/060541 A3, US 7432045 B2
Patent Title Method of inhibiting influenza infection with antiviral peptides
Comment The antiviral peptide showS antiviral activity against a wide range of enveloped and non-enveloped viruses. Examples of enveloped viruses include, but are not limited to, human immunodeficiency virus (HIV), vesicular stomatitis virus (VSV), herpes simplex viruses (HSV-1 and HSV-2), and other herpes viruses, for example, varicella-zoster virus (VZV), EBV, equine herpes virus (EHV), influenza virus and human cytomegalovirus (HCMV). Examples of non-enveloped viruses include, but are not limited to, papilloma virus (PV) and adenoviruses (AV).
Abstract This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral peptides exhibit activity against a broad spectrum of viruses, including enveloped and non-enveloped viruses, and are used in pharmaceutical compositions to prevent and/or treat viral infections.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.