DRAVP ID  DRAVPa1269

Peptide Name   Sequence 28 from Patent US 5616327

Sequence  CATCEQIADSQHRSHRQMA

Sequence Length  19

Source  Synthetic construct

Target Organism  influenza virus

Patent Type  Granted Patent

Publication Date  1997-04-01

Patent No  US 5616327 A

Family Info  CA 2108263 A1, WO 1992/022575 A1, EP 0590055 A1, JP H06508623 A, US 5616327 A, EP 0590055 B1, DE 69223406 D1, DE 69223406 T2

Patent Title  M-protein peptides of influenza virus as antiviral agents

Comment  No comments found in patent

Abstract  Peptides substantially corresponding to the 148-162 region of type A influenza M protein and additionally containing at least one amino acid in the 163-166 region are disclosed to have high activity as influenza transcription inhibitors and thus as antiviral agents against influenza virus and other RNA viruses. The modification of these peptides by incorporation into liposomes or by addition of long-chain alkylamino acids is also shown as in the use of all such materials in antiviral drug formulations.