Patent Information


DRAVP ID  DRAVPa1307

Peptide Name   Sequence 8 from Patent US 5447915 A

Sequence  IKILGNQGSTLTKGPYSK

Sequence Length  18

Source  Synthetic construct

Target Organism  HIV

Patent Type  Granted Patent

Publication Date  1995-09-05

Patent No  US 5447915 A

Family Info  CA 2077088 A1, WO 1991/013088 A1, US 5115098 A, EP 0517792 A1, JP H05503535 A, US 5447915 A

Patent Title  Terminally blocked antiviral peptides

Comment  No comments found in patent

Abstract  This invention relates to antiviral peptide compounds and to methods of inhibiting infection of human cells by viruses. This invention pertains more specifically to peptides that are chemically blocked at the amino- and carboxy-termini. In particular the invention relates to peptides comprised of prolylalanine or prolylphenylalanine compounds that have antiviral activity. The invention is specifically directed to methods for preventing infection of human cells in vivo and in vitro with the human immunodeficiency virus HIV-1 and methods for treating human infected with this and other viruses. The invention also relates to the diagnostic and therapeutic use of these antiviral peptide compounds.