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DRAVP ID DRAVPa2146
Peptide Name Sequence 11 from Patent CN111499692B
Sequence KWPFKKS
Sequence Length 7
Source Synthetic peptide
Target Organism SARS-CoV-2
Patent Type Granted Patent
Publication Date 2020-12-04
Patent No CN111499692B
Patent Title Polypeptide of targeting novel coronavirus COVID-29 and application thereof
Comment
Abstract The invention provides a polypeptide of a targeted novel coronavirus COVID-19 and application thereof, wherein the polypeptide comprises an amino acid sequence shown as SEQ ID NO. 1-28; or the polypeptide is a molecule which is obtained by adding 1-20 amino acid polypeptide sequences and/or conjugated connecting carbon chains to the N end and/or the C end of SEQ ID NO. 1-28 and has the activity of targeting coronavirus COVID-19. The invention adopts a one-bead-one-compound (OBOC) combinatorial chemistry method to synthesize a polypeptide library, utilizes the polypeptide library and the S protein on the surface of the novel coronavirus, and the screened polypeptide has strong binding capacity with the S protein of the coronavirus COVID-29, thereby providing a basis for the research and development of novel coronavirus detection reagents and therapeutic drugs.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.