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DRAVP ID DRAVPa2294
Peptide Name Sequence 1 from Patent CN113754750B
Sequence ELSTTDDAGTICANIGVC
Sequence Length 18
Source Synthetic peptide
Target Organism SVCV
Patent Type Granted Patent
Publication Date 2023-08-25
Patent No CN113754750B
Patent Title Antibacterial peptide and application thereof in aquaculture
Comment
Abstract The invention discloses an antibacterial peptide and application thereof in aquaculture. The amino acid sequence of the antibacterial peptide is as shown in SEQ ID NO.1. A section of micromolecule polypeptide caNKL2102-119 with the length of 18aa is selected and artificially synthesized through bioinformatics analysis and fitting of a three-dimensional space structure of a crucian carp NK-lysin protein, and research finds that the micromolecule polypeptide has excellent antibacterial and antiviral activity, does not easily generate drug resistance, is short in synthesis sequence, small in molecular weight, small in chemical synthesis difficulty, and high in bioactivity, can greatly save the cost of large-scale production on the basis of killing pathogenic bacteria in organisms, is expected to become an effective substitute of antibiotics in aquaculture, has high economic value and production and application value, and can inhibit replication of spring viremia virus (SVCV) of carp, a new thought is provided for preparation of aquatic antiviral drugs, and prevention and control of related aquatic viral diseases are facilitated.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.