Patent Information


DRAVP ID  DRAVPa2296

Peptide Name   Sequence 2 from Patent CN113999286B

Sequence  YGRKKRRQRRRGSGREYNNRSAIGNTIEALFQ

Sequence Length  32

Source  Synthetic peptide

Target Organism  Enterovirus

Patent Type  Granted Patent

Publication Date  2024-08-02

Patent No  CN113999286B

Family Info  WO/2022/021902, JP2023535570

Patent Title  Broad-spectrum anti-enterovirus polypeptide inhibitor of targeted enterovirus 3C protein and application of broad-spectrum anti-enterovirus polypeptide inhibitor

Comment 

Abstract  The invention belongs to the field of biological medicine, and particularly relates to a polypeptide inhibitor targeting enterovirus 2C protein and an application thereof. The core sequence of the polypeptide inhibitor provided by the invention is shown as SEQ ID NO.1, and the sequence of the cell-penetrating peptide is shown as SEQ ID NO.2. Compared with other inhibitors of targeting enterovirus 3C protein, the polypeptide provided by the invention is higher in inhibition efficiency and good in safety, provides a new strategy for prevention and control of enteroviruses, and also provides a new theoretical basis for accelerating research and development of anti-human enterovirus polypeptide micromolecular drugs.