DRAVP ID  DRAVPa2348

Peptide Name   Sequence 31 from CN119119255A

Sequence  GYSITSDFA

Sequence Length  9

Source  Synthetic construct

Target Organism  PEDV

Patent Type  Patent Application

Publication Date  2024-12-13

Patent No  CN119119255A

Family Info  CN 119119255 A

Patent Title  Pig acute diarrhea syndrome coronavirus spike protein antigen epitope peptide and monoclonal antibody and application thereof

Comment 

Abstract  The invention belongs to the technical field of biological industry, and particularly relates to a spike protein antigen epitope peptide of porcine acute diarrhea syndrome coronavirus as well as a monoclonal antibody and application of the spike protein antigen epitope peptide. The invention provides an antibody or an antigen binding fragment thereof. A nucleotide sequence of a heavy chain variable region of the antibody or the antigen binding fragment thereof is as shown in SEQ ID NO. 2; the nucleotide sequence of the light chain variable region of the monoclonal antibody is shown as SEQ ID NO. 4. The amino acid sequence of the minimum binding epitope is as shown in SEQ ID NO.22. The antigen epitope is highly conserved in a plurality of different subtypes of SADS-CoV. The antibody can be applied to fundamental research on an SADS-CoV invasive molecular mechanism and provides a good scientific research material for application research on SADS-CoV detection and treatment.