To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
DRAVP ID DRAVPa2353
Peptide Name Sequence 3 from CN119080879A
Sequence FEEMYRHIL
Sequence Length 9
Source Synthetic construct
Target Organism EBOV
Patent Type Patent Application
Publication Date 2024-12-06
Patent No CN119080879A
Family Info CN 119080879 A
Patent Title Purple MHC I dominant epitope peptide of ebola virus nucleoprotein, and coding gene and application thereof
Comment
Abstract The invention belongs to the technical field of pathogenic microorganism immunology, and particularly relates to a generic MHC I dominant epitope peptide of ebola virus nucleoprotein, and a coding gene and application thereof. The amino acid sequence of the dominant epitope peptide is one of SEQ ID NO. 1-4. According to the invention, the prediction, screening and identification of generic MHC class I antigen specific dominant epitopes are carried out on Ebola virus nucleoprotein (EBOV NP), 12 candidate epitopes are obtained and verified, and 4 representatives are selected for experimental verification. In a word, the generic MHC-I immunoreactivity of the EBOV NP is comprehensively evaluated, the immunology characteristics of the EBOV NP are beneficially understood, and guidance is provided for development of EBOV epitope vaccines in the future.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.