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DRAVP ID DRAVPa2459
Peptide Name Sequence 5 from Patent CN117919373A
Sequence PKCPEPCPP
Sequence Length 9
Source Synthetic construct
Target Organism TLR9
Patent Type Patent Application
Publication Date 2024-04-26
Patent No CN117919373A
Family Info CN 117919373 A
Patent Title Application of polypeptide and polypeptide combination in improvement of antiviral immunity
Comment
Abstract The invention belongs to the field of biological medicines, and particularly relates to a polypeptide and an effect of a polypeptide combination in improvement of antiviral immunity. The invention proves that the polypeptide or polypeptide combination containing 9 amino acids (PKCPEPCPP), for example, SPRR2 family polypeptide (such as antibacterial peptide SPRR2A from a host) can effectively activate a natural immune signal channel, can be used as an endogenous agonist of TLR9, is crucial to activation of the SPRR2 family mediated TLR9 signal channel, and has a remarkable effect in the aspect of virus resistance for the first time.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.