DRAVP ID DRAVPa2467
Peptide Name Sequence 1 from Patent CN117659134A
Sequence SDPPVVWLGGRPGDF
Sequence Length 15
Source Synthetic construct
Target Organism ASFV
Patent Type Patent Application
Publication Date 2024-03-12
Patent No CN117659134A
Family Info CN 117659134 A
Patent Title Antigen epitope peptide of African swine fever virus pD205R protein, monoclonal antibody and application of antigen epitope peptide and monoclonal antibody
Comment
Abstract The invention belongs to the field of biotechnology and biomedicine, and particularly discloses an antigen epitope peptide of African swine fever virus pD205R protein, a monoclonal antibody and application of the antigen epitope peptide and the monoclonal antibody. The antigenic epitope of the African swine fever virus pD205R protein provided by the invention is a linear epitope and is located at the 167th to 181th amino acids (namely 167-SDPPVVWLGGRPGDF-181) of the African swine fever virus pD205R protein, and the key amino acids are S167, W173, L174, G175, P178 and D180. Meanwhile, the monoclonal antibody for resisting the African swine fever virus pD205R protein provided by the invention can specifically recognize and combine with the epitope, and can be used for preparing medicines for preventing and/or treating African swine fever virus infection and reagents for detecting and/or diagnosing African swine fever virus infection. And a new thought is provided for vaccine development and serological diagnosis method establishment.