DRAVP ID  DRAVPa2468

Peptide Name   Sequence 1 from Patent CN117659135A

Sequence  DPLASQRDIYY

Sequence Length  11

Source  Synthetic construct

Target Organism  ASFV

Patent Type  Patent Application

Publication Date  2024-03-08

Patent No  CN117659135A

Family Info  CN 117659135 A

Patent Title  Antigen epitope peptide of African swine fever virus pB125R protein, monoclonal antibody and application of antigen epitope peptide and monoclonal antibody

Comment 

Abstract  The invention belongs to the field of biotechnology and biomedicine, and particularly discloses an antigen epitope peptide of African swine fever virus pB125R protein, a monoclonal antibody and application of the antigen epitope peptide and the monoclonal antibody. The antigenic epitope of the African swine fever virus pB125R protein provided by the invention is a B cell linear epitope, and the minimum antigenic epitope is located at the 52nd-62nd amino acids of the African swine fever virus pB125R protein. A mouse model experiment verifies that the antigen epitope has immunocompetence and is highly conserved in different African swine fever virus strains. Meanwhile, the monoclonal antibody for resisting the African swine fever virus pB125R protein and the hybridoma cell strain provided by the invention can specifically recognize and combine the African swine fever virus pB125R protein, and have stronger reaction activity compared with a screened 15A9 antibody; the compound can be used for preparing a reagent for detecting and/or diagnosing African swine fever virus infection and a medicine for preventing and/or treating African swine fever virus infection.