DRAVP ID DRAVPa2481
Peptide Name Sequence 27 from Patent CN117535323A
Sequence ITVATSRT
Sequence Length 8
Source Synthetic construct
Target Organism SARS-CoV-2
Patent Type Patent Application
Publication Date 2024-02-09
Patent No CN117535323A
Family Info CN 117535323 A
Patent Title Recombinant lactic acid bacteria vector for expressing coronavirus M protein epitope peptide, recombinant lactobacillus plantarum and application
Comment
Abstract The invention provides a fusion gene for expressing coronavirus M protein epitope peptide, a recombinant lactic acid bacteria vector, recombinant lactobacillus plantarum and application, and belongs to the technical field of molecular biology. The fusion gene for expressing the coronavirus M protein epitope peptide comprises a gene sequence for coding a signal peptide, a target gene and an SCWA signal peptide. The invention also provides a recombinant lactic acid bacteria vector containing the fusion gene and recombinant lactobacillus plantarum constructed by the recombinant lactic acid bacteria vector, and results show that the recombinant lactobacillus plantarum has high exogenous gene expression efficiency and good immunogenicity, and has high application value in mucosal immunity. And a foundation is laid for developing a novel crown M protein peptide epitope novel nasal drop vaccine.