Patent Information


DRAVP ID  DRAVPa2481

Peptide Name   Sequence 27 from Patent CN117535323A

Sequence  ITVATSRT

Sequence Length  8

Source  Synthetic construct

Target Organism  SARS-CoV-2

Patent Type  Patent Application

Publication Date  2024-02-09

Patent No  CN117535323A

Family Info  CN 117535323 A

Patent Title  Recombinant lactic acid bacteria vector for expressing coronavirus M protein epitope peptide, recombinant lactobacillus plantarum and application

Comment 

Abstract  The invention provides a fusion gene for expressing coronavirus M protein epitope peptide, a recombinant lactic acid bacteria vector, recombinant lactobacillus plantarum and application, and belongs to the technical field of molecular biology. The fusion gene for expressing the coronavirus M protein epitope peptide comprises a gene sequence for coding a signal peptide, a target gene and an SCWA signal peptide. The invention also provides a recombinant lactic acid bacteria vector containing the fusion gene and recombinant lactobacillus plantarum constructed by the recombinant lactic acid bacteria vector, and results show that the recombinant lactobacillus plantarum has high exogenous gene expression efficiency and good immunogenicity, and has high application value in mucosal immunity. And a foundation is laid for developing a novel crown M protein peptide epitope novel nasal drop vaccine.