DRAVP ID  DRAVPa2517

Peptide Name   Sequence 1 from Patent CN117343148A

Sequence  LKKLKWLAHRLKGMLKKYLKPTAASS

Sequence Length  26

Source  Synthetic construct

Target Organism  CHIKV,HTNV,DENV,HSV

Patent Type  Patent Application

Publication Date  2024-01-05

Patent No  CN117343148A

Family Info  CN 117343148 A

Patent Title  Antibacterial peptide and application thereof in preparation of antibacterial drugs or antiviral drugs

Comment 

Abstract  The invention discloses an antibacterial peptide and application thereof in preparation of an antibacterial drug or an antiviral drug. The amino acid sequence of the antibacterial peptide is as shown in SEQ ID NO.1. The amino acid sequence of the antibacterial peptide is as shown in SEQ ID NO.2. The MIC of the antibacterial peptide disclosed by the invention on escherichia coli, staphylococcus aureus, pseudomonas aeruginosa and acinetobacter baumannii is less than or equal to 20 mu g/mL; multiple drug-resistant escherichia coli, drug-resistant staphylococcus aureus, drug-resistant pseudomonas aeruginosa and drug-resistant acinetobacter baumannii can be inhibited; the inhibition effect on drug-resistant acinetobacter baumannii which is focused by WHO is outstanding; the antibacterial peptide disclosed by the invention is good in safety and has relatively low cytotoxicity and hemolytic activity, and the animal toxicity is lower than that of the existing clinical antibacterial peptide polymyxin B; the compound also has a broad-spectrum antiviral effect, and has an inhibiting effect on hantavirus, chikungunya virus, herpes simplex virus type 1 or dengue virus type 2.