Patent Information


DRAVP ID  DRAVPa2625

Peptide Name   SEQ ID NO:7

Sequence  SNNTIAIPTNFSISITTEVM

Sequence Length  20

Source  Synthetic construct

Target Organism  SARS-CoV

Patent Type  Granted Patent

Publication Date  2009-02-22

Patent No  US7491489

Family Info  CN2005101315809A

Patent Title  Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof

Comment 

Abstract  The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.