DRAVP ID DRAVPa2626
Peptide Name SEQ ID NO:4
Sequence PALNCYWPLNDYGFYTTSGI
Sequence Length 20
Source Synthetic construct
Target Organism SARS-CoV
Patent Type Granted Patent
Publication Date 2009-02-23
Patent No US7491489
Family Info CN2005101315809A
Patent Title Synthetic peptide targeting critical sites on the SARS-associated coronavirus spike protein responsible for viral infection and method of use thereof
Comment
Abstract The present invention provides methods for locating critical portions or sites on the spike protein (S protein) of SARS-associated coronavirus (SARS-CoV) responsible for the viral infection that causes Severe Acute Respiratory Syndrome (SARS). The present invention also provides new synthetic peptides targeting such critical portions or sites of the S protein of SARS-CoV for preventing or treating of SARS-CoV infection in a subject. The present invention further provides methods of testing antiviral activity exerted by antiviral agents using real-time quantitative PCR.