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General Information
DRAVPR ID DRAVPR0016
Name Trem-like transcript 4 protein(TLT-4)
Sequence
Sequence Length 263
Source Mus musculus (Mouse)
UniProt ID Q3LRV9
Gene Treml4
Activity Information
Target Organism IAV
Activity [Ref.25848864]TREML4 plays an important role in the regulation of TLR7 signaling and that its expression in vivo is required for antiviral host defense to influenza and for promotion of TLR7-mediated autoimmune disease.
Structure Information
PDB ID None
Predicted Structure Download AF-Q3LRV9-F1
Modification ①Glycosylation of Asn at position 100.②There is a disulfide bond between Cys47 and Cys116.
Comment
No comments found in the entry
Literature Information
Literature 1
Title The receptor TREML4 amplifies TLR7-mediated signaling during antiviral responses and autoimmunity.
Pubmed ID 25848864
Author Ramirez-Ortiz ZG, Prasad A, Griffith JW, Pendergraft WF 3rd, Cowley GS, Root DE, Tai M, Luster AD, El Khoury J, Hacohen N, Means TK.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.