To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0020
Name Inactive 2'-5'-oligoadenylate synthase 1B
Sequence
Sequence Length 376
Source Mus musculus (Mouse)
UniProt ID Q60856
Gene Oas1b
Activity Information
Target Organism WNV
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q60856-F1
Modification No modifications on the sequence.
Comment
Oas1b-dependent antiviral activity is restricted to the early stages of WNV replication,the Oas1b-mediated inhibition of viral protein synthesis and the subsequent suppression of viral growth are due to a lack of accumulation of viral RNA inside cells.
Literature Information
Literature 1
Title The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells.
Pubmed ID 16371364
Author Kajaste-Rudnitski A, Mashimo T, Frenkiel MP, Guénet JL, Lucas M, Desprès P.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.