General Information


DRAVPR ID  DRAVPR0038

Name   DNA dC->dU-editing enzyme APOBEC-3

Sequence 

Sequence Length  440

Source  Mus musculus (Mouse)

UniProt ID Q99J72

Gene Apobec3



Activity Information


Target Organism  MMTV,FrMLV

Activity 

  • [Ref.17259974]mouse mammary tumour virus(MMTV):APOBEC3 inhibits mouse mammary tumour virus replication.
  • [Ref.18786991]friend leukemia virus(FrMLV):Mouse APOBEC3 restricts friend leukemia virus infection in vivo.



Structure Information


PDB ID  None

Predicted Structure Download  AF-Q99J72-F1

';

Modification  No modifications on the sequence.



Comment


TRIM52 is a RING-type E3 ligase, the RING domain of TRIM52 is required for TRIM52 to control JEV replication.TRIM22 is endowed with a potent capacity to repress various viral infections, including HIV, HBV, EMCV, and IAV.



Literature Information


Literature 1

Title   APOBEC3 inhibits mouse mammary tumour virus replication in vivo. 

Pubmed ID   17259974

Author   Okeoma CM, Lovsin N, Peterlin BM, Ross SR.

Literature 2

Title   Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.

Pubmed ID   18786991

Author   Takeda E, Tsuji-Kawahara S, Sakamoto M, Langlois MA, Neuberger MS, Rada C, Miyazawa M.