To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0040
Name Interferon-induced transmembrane protein 1
Sequence
Sequence Length 106
Source Mus musculus (Mouse)
UniProt ID Q9D103
Gene Ifitm1
Activity Information
Target Organism MERS-CoV
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q9D103-F1
Modification The Cys at position 49,50,83 indicates S-palmitoyl cysteine.
Comment
Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV) and West Nile virus (WNV).
Literature Information
Literature 1
Title IFITM proteins inhibit entry driven by the MERS-coronavirus spike protein: evidence for cholesterol-independent mechanisms.
Pubmed ID 25256397
Author Wrensch F, Winkler M, Pöhlmann S.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.