General Information


DRAVPR ID  DRAVPR0043

Name   Vesicle-associated membrane protein 8

Sequence 

Sequence Length  100

Source  Homo sapiens (Human)

UniProt ID Q9BV40

Gene VAMP8



Activity Information


Target Organism  WNV

Activity 

  • [Ref.31694946]West Nile virus(WNV):VAMP8 contributes to the TRIM6-mediated type I interferon antiviral response during west nile virus infection.



Structure Information


PDB ID  4WY4  7BV6 

Predicted Structure Download  AF-Q9BV40-F1

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Modification  ①Phosphorylation of Ser at position 5,18,55.②The N-terminal is acetylation.③Phosphorylation of Thr at position 28,48,54.



Comment


Cyclophilin A regulates the life cycle of several viruses including human immunodeficiency virus type 1, vesicular stomatitis virus, vaccinia virus (VV), hepatitis C virus



Literature Information


Literature 1

Title   VAMP8 Contributes to the TRIM6-Mediated Type I Interferon Antiviral Response during West Nile Virus Infection.

Pubmed ID   31694946

Author   van Tol S, Atkins C, Bharaj P, Johnson KN, Hage A, Freiberg AN, Rajsbaum R.