General Information


DRAVPR ID  DRAVPR0061

Name   Interferon-induced GTP-binding protein Mx1

Sequence 

Sequence Length  631

Source  Mus musculus (Mouse)

UniProt ID P09922

Gene Mx1



Activity Information


Target Organism  IAV,IBV,THOV

Activity 

  • [Ref.21166595]influenza A virus(IAV)/Thogoto virus(THOV)/influenza B virus (IBV)/:exhibits antiviral activity against IAV,IBV and THOV.



Structure Information


PDB ID  None

Predicted Structure Download  AF-P09922-F1

';

Modification  No modifications on the sequence.



Comment


poMx1 decreases or delays NP synthesis, and inhibits production of progeny viral particles and hampers viral infection at an early stage.



Literature Information


Literature 1

Title   Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity. 

Pubmed ID   21166595

Author   Haller O, Kochs G.