General Information


DRAVPR ID  DRAVPR0068

Name   Interferon-induced GTP-binding protein Mx2

Sequence 

Sequence Length  711

Source  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID Q9N0Y2

Gene MX2



Activity Information


Target Organism  VSV

Activity 

  • [Ref.15767791]vesicular stomatitis virus (VSV):Mx2 had an antiviral activity against recombinant vesicular stomatitis virus (VSV).



Structure Information


PDB ID  None

Predicted Structure Download  AF-Q9N0Y2-F1

';

Modification  No modifications on the sequence.



Comment


The protein target viruses belong to families which include retroviridae: human immunodeficiency virus type 1 (HIV-1) and moloney and murine leukemia virus (MoMLV), filoviridae: ebola virus (EBOV) and marburg virus (MARV), togaviridae: sindbis virus (SINV) and Ross river virus (RRV).



Literature Information


Literature 1

Title   Intracellular localization and antiviral property of canine Mx proteins.

Pubmed ID   15767791

Author   Nakamura T, Asano A, Okano S, Ko JH, Kon Y, Watanabe T, Agui T.