General Information
DRAVPR ID DRAVPR0074
Name Interferon gamma(IFN-gamma)
Sequence
Sequence Length 155
Source Mus musculus (Mouse)
UniProt ID P01580
Gene Ifng
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.8456301]Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antiviral responses by activating effector immune cells and enhancing antigen presentation.
Structure Information
PDB ID None
Predicted Structure Download AF-P01580-F1
Modification Glycosylation of Asn at position 38,90.
Comment
TRIM56 exhibits a broad antiviral activity against bovine viral diarrhea virus (BVDV), yellow fever virus (YFV), dengue virus serotype 2 (DENV2), human coronavirus virus (HCoV), and influenza A and B viruses.TRIM56 had no effect on the replication of vesicular stomatitis virus (VSV) and HCV.
Literature Information
Literature 1
Title Immune response in mice that lack the interferon-gamma receptor.
Pubmed ID 8456301
Author Huang S, Hendriks W, Althage A, Hemmi S, Bluethmann H, Kamijo R, Vilcek J, Zinkernagel RM, Aguet M.