General Information


DRAVPR ID  DRAVPR0074

Name   Interferon gamma(IFN-gamma)

Sequence 

Sequence Length  155

Source  Mus musculus (Mouse)

UniProt ID P01580

Gene Ifng



Activity Information


Target Organism  No specific virus mentioned in the entry

Activity  [Ref.8456301]Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antiviral responses by activating effector immune cells and enhancing antigen presentation.



Structure Information


PDB ID  None

Predicted Structure Download  AF-P01580-F1

';

Modification  Glycosylation of Asn at position 38,90.



Comment


TRIM56 exhibits a broad antiviral activity against bovine viral diarrhea virus (BVDV), yellow fever virus (YFV), dengue virus serotype 2 (DENV2), human coronavirus virus (HCoV), and influenza A and B viruses.TRIM56 had no effect on the replication of vesicular stomatitis virus (VSV) and HCV.



Literature Information


Literature 1

Title   Immune response in mice that lack the interferon-gamma receptor. 

Pubmed ID   8456301

Author   Huang S, Hendriks W, Althage A, Hemmi S, Bluethmann H, Kamijo R, Vilcek J, Zinkernagel RM, Aguet M.