General Information


DRAVPR ID  DRAVPR0077

Name   2'-5'-oligoadenylate synthase 2

Sequence 

Sequence Length  719

Source  Homo sapiens (Human)

UniProt ID P29728

Gene OAS2



Activity Information


Target Organism  No specific virus mentioned in the entry

Activity  [Ref.21142819]The 2'-5' oligoadenylate synthetases (OAS) can mediate the antiviral effect via the classical RNASEL-dependent pathway or an alternative antiviral pathway independent of RNASEL.



Structure Information


PDB ID  None

Predicted Structure Download  No predicted structure information available for the entry

';

Modification  ①The Gly at position 2 indicates N-myristoyl glycine.②Acetylation of Lys at position 378.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.

Pubmed ID   21142819

Author   Kristiansen H, Gad HH, Eskildsen-Larsen S, Despres P, Hartmann R.