General Information
DRAVPR ID DRAVPR0077
Name 2'-5'-oligoadenylate synthase 2
Sequence
Sequence Length 719
Source Homo sapiens (Human)
UniProt ID P29728
Gene OAS2
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.21142819]The 2'-5' oligoadenylate synthetases (OAS) can mediate the antiviral effect via the classical RNASEL-dependent pathway or an alternative antiviral pathway independent of RNASEL.
Structure Information
PDB ID None
Predicted Structure Download No predicted structure information available for the entry
Modification ①The Gly at position 2 indicates N-myristoyl glycine.②Acetylation of Lys at position 378.
Comment
No comments found in the entry
Literature Information
Literature 1
Title The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.
Pubmed ID 21142819
Author Kristiansen H, Gad HH, Eskildsen-Larsen S, Despres P, Hartmann R.