General Information


DRAVPR ID  DRAVPR0082

Name   Guanylate-binding protein 1

Sequence 

Sequence Length  592

Source  Homo sapiens (Human)

UniProt ID P32455

Gene GBP1



Activity Information


Target Organism  influenza virus

Activity 

  • [Ref.22106366]influenza virus:GBP-1 mediates anti-influenza activity through inhibition of viral transcription and replication.



Structure Information


PDB ID  1DG3  1F5N  2B8W  6K1Z 

Predicted Structure Download  AF-P32455-F1

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Modification  The Cys at position 589 indicates S-farnesyl cysteine.



Comment


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Literature Information


Literature 1

Title   A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication.

Pubmed ID   22106366

Author   Nordmann A, Wixler L, Boergeling Y, Wixler V, Ludwig S.