General Information
DRAVPR ID DRAVPR0085
Name Interferon alpha-4
Sequence
Sequence Length 189
Source Homo sapiens (Human)
UniProt ID P05014
Gene IFNA4
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.9334213]IFN-alpha have antiviral activities.
Structure Information
PDB ID None
Predicted Structure Download AF-P05014-F1
Modification There are two disulfide bonds between Cys24 and Cys122, Cys52 and Cys162.
Comment
No comments found in the entry
Literature Information
Literature 1
Title A region of the beta subunit of the interferon alpha receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state.
Pubmed ID 9334213
Author Domanski P, Fish E, Nadeau OW, Witte M, Platanias LC, Yan H, Krolewski J, Pitha P, Colamonici OR.