General Information


DRAVPR ID  DRAVPR0087

Name   Interferon beta

Sequence 

Sequence Length  187

Source  Homo sapiens (Human)

UniProt ID P01574

Gene IFNB1



Activity Information


Target Organism  No specific virus mentioned in the entry

Activity  [Ref.6171735]IFN-beta have antiviral activities.



Structure Information


PDB ID  1AU1 

Predicted Structure Download  AF-P01574-F1

';

Modification  ①There is a disulfide bond between Cys52 and Cys162.②Phosphorylation of Thr at position 24.③Glycosylation of Asn at position 101.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   A single amino acid change in IFN-beta1 abolishes its antiviral activity.

Pubmed ID   6171735

Author   Shepard HM, Leung D, Stebbing N, Goeddel DV.