To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0090
Name T-box transcription factor TBX21
Sequence
Sequence Length 530
Source Mus musculus (Mouse)
UniProt ID Q9JKD8
Gene Tbx21(Tbet)
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.27430722]B cell specific loss of T-bet prevents control of persisting viral infection.T-bet is a universal controller of antiviral immunity across multiple immune lineages.
Structure Information
PDB ID 5T1J
Predicted Structure Download AF-Q9JKD8-F1
Modification ①Phosphorylation of Ser at position 52,224,508.②Phosphorylation of Tyr at position 76,117,219,265,304,525.③Phosphorylation of Thr at position 55,302.
Comment
No comments found in the entry
Literature Information
Literature 1
Title Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection.
Pubmed ID 27430722
Author Barnett BE, Staupe RP, Odorizzi PM, Palko O, Tomov VT, Mahan AE, Gunn B, Chen D, Paley MA, Alter G, Reiner SL, Lauer GM, Teijaro JR, Wherry EJ.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.