General Information
DRAVPR ID DRAVPR0112
Name NFX1-type zinc finger-containing protein 1
Sequence
Sequence Length 1909
Source Mus musculus (Mouse)
UniProt ID Q8R151
Gene Znfx1
Activity Information
Target Organism VSV, EMCV, SeV
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q8R151-F1
Modification No modifications on the sequence.
Comment
zinc finger NFX1-type containing 1 (ZNFX1), a helicase SF1, is an interferon (IFN)-stimulated, mitochondrial-localised dsRNA sensor that specifically restricts the replication of RNA viruses.
Literature Information
Literature 1
Title Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS.
Pubmed ID 31685995
Author Wang Y, Yuan S, Jia X, Ge Y, Ling T, Nie M, Lan X, Chen S, Xu A.