General Information
DRAVPR ID DRAVPR0116
Name E3 ubiquitin-protein ligase TRIM11
Sequence
Sequence Length 468
Source Homo sapiens (Human)
UniProt ID Q96F44
Gene TRIM11
Activity Information
Target Organism HIV-1
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q96F44-F1
Modification Phosphorylation of Ser at position 85.
Comment
Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression.
Literature Information
Literature 1
Title TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
Pubmed ID 18248090
Author Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W.