To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0117
Name 2'-5'-oligoadenylate synthase-like protein 2(p54 OASL)
Sequence
Sequence Length 508
Source Mus musculus (Mouse)
UniProt ID Q9Z2F2
Gene Oasl2
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.12799444]mOasl2 can active Rnase L. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication.
Structure Information
PDB ID None
Predicted Structure Download AF-Q9Z2F2-F1
Modification No modifications on the sequence.
Comment
mOasl2 protein is Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response.
Literature Information
Literature 1
Title Characterization of the 2'-5'-oligoadenylate synthetase ubiquitin-like family
Pubmed ID 12799444
Author Eskildsen S, Justesen J, Schierup MH, Hartmann R.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.