General Information
DRAVPR ID DRAVPR0120
Name Interferon-induced protein with tetratricopeptide repeats 2
Sequence
Sequence Length 472
Source Mus musculus (Mouse)
UniProt ID Q64112
Gene Ifit2
Activity Information
Target Organism VSV
Activity
Structure Information
PDB ID None
Predicted Structure Download AF-Q64112-F1
Modification The N-terminal is acetylation.
Comment
Ifit2 failed to protect mice from another neurotropic virus, encephalomyocarditis virus, nor was it necessary for protecting organs other than brain from infection by VSV.
Literature Information
Literature 1
Title Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis.
Pubmed ID 22615570
Author Fensterl V, Wetzel JL, Ramachandran S, Ogino T, Stohlman SA, Bergmann CC, Diamond MS, Virgin HW, Sen GC.