General Information


DRAVPR ID  DRAVPR0121

Name   2'-5'-oligoadenylate synthase 3

Sequence 

Sequence Length  1138

Source  Mus musculus (Mouse)

UniProt ID Q8VI93

Gene Oas3 (oasl10)



Activity Information


Target Organism  No specific virus mentioned in the entry

Activity  [Ref.12396720]mOas3 can active Rnase L. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication.



Structure Information


PDB ID  None

Predicted Structure Download  AF-Q8VI93-F1

';

Modification  No modifications on the sequence.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family.

Pubmed ID   12396720

Author   Kakuta S, Shibata S, Iwakura Y.