General Information
DRAVPR ID DRAVPR0121
Name 2'-5'-oligoadenylate synthase 3
Sequence
Sequence Length 1138
Source Mus musculus (Mouse)
UniProt ID Q8VI93
Gene Oas3 (oasl10)
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.12396720]mOas3 can active Rnase L. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication.
Structure Information
PDB ID None
Predicted Structure Download AF-Q8VI93-F1
Modification No modifications on the sequence.
Comment
No comments found in the entry
Literature Information
Literature 1
Title Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family.
Pubmed ID 12396720
Author Kakuta S, Shibata S, Iwakura Y.