To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0135
Name Interferon-stimulated gene 20 kDa protein
Sequence
Sequence Length 300
Source Mus musculus (Mouse)
UniProt ID Q9JL16
Gene Isg20
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.30232164]Ectopic expression of the interferon-induced 20-kDa exonuclease ISG20 suppressed replication of chikungunya virus and Venezuelan equine encephalitis virus, two mosquito-vectored RNA alphaviruses.
Structure Information
PDB ID None
Predicted Structure Download AF-Q9JL16-F1
Modification No modifications on the sequence.
Comment
ISG20 upregulated IFIT1 genes and inhibited translation of the alphavirus genome.
Literature Information
Literature 1
Title The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins
Pubmed ID 30232164
Author Weiss CM, Trobaugh DW, Sun C, Lucas TM, Diamond MS, Ryman KD, Klimstra WB.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.