To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.
General Information
DRAVPR ID DRAVPR0137
Name Interferon-induced helicase C domain-containing protein 1
Sequence
Sequence Length 1025
Source Mus musculus (Mouse)
UniProt ID Q8R5F7
Gene Ifih1
Activity Information
Target Organism No specific virus mentioned in the entry
Activity [Ref.19656871]plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type I interferons
Structure Information
PDB ID 3TS9 6G19 6GKM 7BKQ 7NGA 7BKP
Predicted Structure Download AF-Q8R5F7-F1
Modification Phosphorylation of Ser at position 289, 291, 302, 645, 648, 828.
Comment
No comments found in the entry
Literature Information
Literature 1
Title Activation of MDA5 requires higher-order RNA structures generated during virus infection.
Pubmed ID 19656871
Author Pichlmair A, Schulz O, Tan CP, Rehwinkel J, Kato H, Takeuchi O, Akira S, Way M, Schiavo G, Reis e Sousa C.
Literature 2
Title Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity.
Pubmed ID 17942531
Author Loo YM, Fornek J, Crochet N, Bajwa G, Perwitasari O, Martinez-Sobrido L, Akira S, Gill MA, García-Sastre A, Katze MG, Gale M Jr.
To the extent possible under law, the person who associated CC0 with this work has waived all copyright and related or neighboring rights to this work.