General Information


DRAVPR ID  DRAVPR0140

Name   Pokeweed antiviral Protein(PAP)

Sequence 

Sequence Length  262

Source  leaves of pokeweed

UniProt ID P10297

Gene PAP1



Activity Information


Target Organism  HIV-1

Activity 

  • [Ref:10493577]TMV:Possesses antiviral potency. Inhibits viral infection of plants (tobacco mosaic virus)



Structure Information


PDB ID  1QCG 

Predicted Structure Download  No predicted structure information available for the entry

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Modification  No modifications on the sequence.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   X-ray crystallographic analysis of the structural basis for the interactions of pokeweed antiviral protein with its active site inhibitor and ribosomal RNA substrate analogs

Pubmed ID   10493577

Author   Kurinov, I. V., Myers, D. E., Irvin, J. D., & Uckun, F. M

Literature 2

Title   Pokeweed antiviral protein isoforms PAP-I, PAP-II, and PAP-III depurinate RNA of human immunodeficiency virus (HIV)-1

Pubmed ID   10403789

Author   Rajamohan, F., Venkatachalam, T. K., Irvin, J. D., & Uckun, F. M. (1999).