General Information


DRAVPR ID  DRAVPR0146

Name   229E-HR1P

Sequence 

Sequence Length  56

Source  S2 subunit of HCoV-229E

UniProt ID P15423

Gene S2



Activity Information


Target Organism  SARS-CoV

Activity 

  • [Ref:29415501]SARS-CoV:5.7,13.2 μM (IC50). Neither 229E-HR1P nor 229E-HR2P had significant cytotoxicity to these cells at concentrations up to 1,000 μM



Structure Information


PDB ID  5YL9  5ZHY 

Predicted Structure Download  No predicted structure information available for the entry

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Modification  No modifications on the sequence.



Comment


No comments found in the entry



Literature Information


Literature 1

Title   Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains

Pubmed ID   29415501

Author   Xia, S., Xu, W., Wang, Q., Wang, C., Hua, C., Li, W., Lu, L., & Jiang, S. (2018)